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Module 1
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BP
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GO:0050855
|
regulation of B cell receptor signaling pathway
|
LYN, PTPN6, PTPRC
|
3.44E-06
|
|
BP
|
GO:0050866
|
negative regulation of cell activation
|
CCR2, CNR1, LYN, PDGFRA, PTPN6
|
4.23E-06
|
|
BP
|
GO:0002703
|
regulation of leukocyte mediated immunity
|
BTK, CCR2, LYN, PTPN6, PTPRC
|
4.36E-06
|
|
BP
|
GO:0050853
|
B cell receptor signaling pathway
|
BTK, LYN, PTPN6, PTPRC
|
7.04E-06
|
|
BP
|
GO:0045577
|
regulation of B cell differentiation
|
BTK, PTPN6, PTPRC
|
1.56E-05
|
|
Module 2
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|
BP
|
GO:0002431
|
Fc receptor mediated stimulatory signaling pathway
|
FYN, HCK, ITPR2, ITPR3, RAC1, SYK, VAV1
|
6.58E-08
|
|
BP
|
GO:0038094
|
Fc-gamma receptor signaling pathway
|
FYN, HCK, ITPR2, ITPR3, RAC1, SYK, VAV1
|
8.67E-08
|
|
BP
|
GO:0002433
|
immune response-regulating cell surface receptor signaling pathway involved in phagocytosis
|
FYN, HCK, ITPR2, ITPR3, RAC1, SYK, VAV1
|
1.68E-07
|
|
BP
|
GO:0038096
|
Fc-gamma receptor signaling pathway involved in phagocytosis
|
FYN, HCK, ITPR2, ITPR3, RAC1, SYK, VAV1
|
1.68E-07
|
|
BP
|
GO:0048010
|
vascular endothelial growth factor receptor signaling pathway
|
FYN, ITPR2, ITPR3, RAC1, VAV1
|
4.86E-06
|
|
Module 4
|
|
BP
|
GO:2000379
|
positive regulation of reactive oxygen species metabolic process
|
CYBA, ICAM1, INSR, KLF4, TGFB1, TSPO
|
1.59E-07
|
|
BP
|
GO:0043200
|
response to amino acid
|
CFL1, COL1A1, COL6A1, CYBA, ICAM1, MMP2
|
2.18E-07
|
|
BP
|
GO:1903426
|
regulation of reactive oxygen species biosynthetic process
|
CYBA, ICAM1, INSR, KLF4, TSPO
|
8.46E-07
|
|
BP
|
GO:2000377
|
regulation of reactive oxygen species metabolic process
|
CYBA, ICAM1, INSR, KLF4, TGFB1, TSPO
|
8.80E-07
|
|
BP
|
GO:0022617
|
extracellular matrix disassembly
|
COL1A1, COL6A1, COL8A1, LCP1, MMP2, TGFB1
|
8.92E-07
|
|
Module 6
|
|
BP
|
GO:0002220
|
innate immune response activating cell surface receptor signaling pathway
|
ICAM3, IL1B, NFKB1, PSMA6, PSMB8, PSMD8, TLR2
|
1.52E-07
|
|
BP
|
GO:0002223
|
stimulatory C-type lectin receptor signaling pathway
|
ICAM3, IL1B, NFKB1, PSMA6, PSMB8, PSMD8
|
2.33E-06
|
|
BP
|
GO:0050764
|
regulation of phagocytosis
|
CNN2, FGR, IL1B, ITGAV
|
8.97E-05
|
|
BP
|
GO:0051437
|
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
|
ANAPC5, PSMA6, PSMB8, PSMD8
|
1.01E-04
|
|
BP
|
GO:0002479
|
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
|
ITGAV, PSMA6, PSMB8, PSMD8
|
1.06E-04
|
|
Module 12
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|
BP
|
GO:0045740
|
positive regulation of DNA replication
|
BMP4, CDK1, TIMP1
|
6.24E-05
|
|
BP
|
GO:0090100
|
positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
|
ACVR2B, BMP4, ENG
|
9.44E-05
|
|
BP
|
GO:0045446
|
endothelial cell differentiation
|
ACVR2B, BMP4, ENG
|
9.74E-05
|
|
BP
|
GO:0060840
|
artery development
|
ACVR2B, BMP4, ENG
|
1.09E-04
|
